Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Abiraterone
Drug ID BADD_D00014
Description Abiraterone is a derivative of steroidal progesterone and is an innovative drug that offers clinical benefit to patients with hormone refractory prostate cancer. Abiraterone is administered as an acetate salt prodrug because it has a higher bioavailability and less susceptible to hydrolysis than abiraterone itself. FDA approved on April 28, 2011.
Indications and Usage Used in combination with prednisone for the treatment of metastatic, castration-resistant prostate cancer.
Marketing Status Not Available
ATC Code Not Available
DrugBank ID DB05812
KEGG ID Not Available
MeSH ID C089740
PubChem ID 132971
TTD Drug ID D02STN
NDC Product Code 17337-0082; 30007-838; 42291-073; 60687-455; 69238-1165; 42291-024; 69238-1754; 54893-0070
Synonyms abiraterone | 17-(3-pyridyl)androsta-5,16-dien-3beta-ol | CB-7598 | CB 7598 | CB7598
Chemical Information
Molecular Formula C24H31NO
CAS Registry Number 154229-19-3
SMILES CC12CCC(CC1=CCC3C2CCC4(C3CC=C4C5=CN=CC=C5)C)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cataract06.06.01.001--
Cellulitis11.02.01.001; 23.09.01.001--Not Available
Cerebral haemorrhage17.08.01.003; 24.07.04.001--Not Available
Cerebral infarction17.08.01.004; 24.04.06.002--Not Available
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chest discomfort02.02.02.009; 08.01.08.019; 22.02.08.001--Not Available
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.003--Not Available
Chills08.01.09.001; 15.05.03.016--
Cholecystitis09.03.01.001--
Cholelithiasis09.03.01.002--Not Available
Chromaturia20.02.01.0020.005884%
Chronic obstructive pulmonary disease22.03.01.007--Not Available
Clostridium difficile colitis07.19.01.004; 11.02.02.004--Not Available
Cold sweat08.01.03.024; 23.02.03.002--Not Available
Colitis07.08.01.001--
Colon cancer07.21.01.001; 16.13.01.0010.001343%Not Available
Coma hepatic09.01.03.005; 17.02.09.0020.000384%Not Available
Completed suicide08.04.01.010; 19.12.01.001--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.0010.051484%
Coordination abnormal17.02.02.004--Not Available
Coronary artery occlusion02.02.01.006; 24.04.04.0130.001471%Not Available
Coronary artery stenosis02.02.01.010; 24.04.04.0170.001471%Not Available
Cough22.02.03.001--
Cushing's syndrome05.01.01.001; 14.11.01.007; 19.07.03.002; 24.08.04.0010.002206%Not Available
Cushingoid05.01.01.002; 14.11.01.006; 19.07.03.001; 24.08.02.0040.001471%
Cystitis11.01.14.001; 20.03.02.0020.011032%
Deafness04.02.01.001--Not Available
Death08.04.01.0010.226403%
Decubitus ulcer23.03.11.0060.001471%Not Available
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