Drug Name |
Abacavir sulfate |
Drug ID |
BADD_D00010 |
Description |
Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir. |
Indications and Usage |
For the treatment of HIV-1 infection, in combination with other antiretroviral agents. |
Marketing Status |
approved; investigational |
ATC Code |
J05AF06 |
DrugBank ID |
DB01048
|
KEGG ID |
D00891
|
MeSH ID |
C106538
|
PubChem ID |
9843042
|
TTD Drug ID |
D0A4IJ
|
NDC Product Code |
68554-0063; 53104-7558; 65862-089; 61876-0718; 65571-0012; 49702-222; 63379-049; 65085-0024; 65862-256; 82245-0207; 64980-405; 17337-0001; 61187-010; 49702-221; 65015-640; 0378-4105; 51079-204; 68554-0032 |
UNII |
J220T4J9Q2
|
Synonyms |
abacavir | 1592U89 | abacavir sulfate | Ziagen | (1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene-1-methanol | abacavir succinate |