Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Vogt-Koyanagi-Harada disease
ADR ID BADD_A11176
ADR Hierarchy
10      Immune system disorders
10.02      Immune disorders NEC
10.02.01      Immune and associated conditions NEC
10.02.01.105      Vogt-Koyanagi-Harada disease
06      Eye disorders
06.04      Ocular infections, irritations and inflammations
06.04.03      Iris and uveal tract infections, irritations and inflammations
06.04.03.009      Vogt-Koyanagi-Harada disease
17      Nervous system disorders
17.06      Central nervous system infections and inflammations
17.06.01      Central nervous system inflammatory disorders NEC
17.06.01.006      Vogt-Koyanagi-Harada disease
Description A syndrome characterized by bilateral granulomatous UVEITIS with IRITIS and secondary GLAUCOMA, premature ALOPECIA, symmetrical VITILIGO, poliosis circumscripta (a strand of depigmented hair), HEARING DISORDERS, and meningeal signs (neck stiffness and headache). Examination of the cerebrospinal fluid reveals a pattern consistent with MENINGITIS, ASEPTIC. (Adams et al., Principles of Neurology, 6th ed, p748; Surv Ophthalmol 1995 Jan;39(4):265-292) [MeSH]
MedDRA Code 10082001
MeSH ID D014607; D014607; D014607
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Harada's disease | Vogt-Koyanagi syndrome | Vogt-Koyanagi-Harada syndrome | Uveoencephalitis | Uveomeningitis syndrome | Vogt-Koyanagi-Harada disease | Uveomeningoencephalitic Syndrome | Syndrome, Uveomeningoencephalitic | Uveomeningoencephalitis | Uveomeningoencephalitides | VKH Syndrome | Syndrome, VKH | Syndrome, VKH (Vogt Koyanagi Harada) | VKH Syndrome (Vogt Koyanagi Harada) | Vogt-Koyanagi-Harada Disease | Disease, Vogt-Koyanagi-Harada | Vogt Koyanagi Harada Disease | VKH (Vogt Koyanagi Harada) Syndrome | Vogt-Koyanagi-Harada Syndrome | Syndrome, Vogt-Koyanagi-Harada | Vogt Koyanagi Harada Syndrome | Syndrome, Vogt Koyanagi Harada
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00551Cyclosporine0.000111%
BADD_D01136Imatinib0.000168%
BADD_D01167Interferon alfa-2b--
BADD_D01696Peginterferon alfa-2b--
BADD_D01933Ribavirin0.007912%
BADD_D02272Triamcinolone acetonide0.000041%
BADD_D02344Vemurafenib0.000112%
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