Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Oncocytoma
ADR ID BADD_A10555
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.02      Miscellaneous and site unspecified neoplasms benign
16.02.02      Neoplasms benign site unspecified NEC
16.02.02.016      Oncocytoma
Description A usually benign glandular tumor composed of oxyphil cells, large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askanazy cells. | A subtype of follicular adenoma in the THYROID GLAND. The Hurthle cell tumor is composed predominantly (at least 75%) or entirely of oxyphil cells. Hurthle cell neoplasms can be divided into benign and malignant categories. Malignant Hurthle cell carcinoma usually appear in patients over 60 years of age and are radioresistant. [MeSH]
MedDRA Code 10048757
MeSH ID D018249
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Oncocytoma | Oxyphil adenoma | Adenoma, Oxyphilic | Oxyphilic Adenoma | Hurthle Cell Tumor | Huerthle Cell Tumor
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01303Lithium carbonate0.001338%
BADD_D01304Lithium cation0.000192%
BADD_D01401Metformin0.000005%
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