Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Malignant oligodendroglioma
ADR ID BADD_A10353
ADR Hierarchy
17      Nervous system disorders
17.20      Nervous system neoplasms malignant and unspecified NEC
17.20.02      Glial tumours malignant
17.20.02.010      Malignant oligodendroglioma
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.30      Nervous system neoplasms malignant and unspecified NEC
16.30.02      Glial tumours malignant
16.30.02.010      Malignant oligodendroglioma
Description A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2052; Adams et al., Principles of Neurology, 6th ed, p655) [MeSH]
MedDRA Code 10026659
MeSH ID D009837
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Malignant oligodendroglioma | Oligodendroglioma malignant | Anaplastic oligodendroglioma | IDH-mutant and 1p/19q co-deleted oligodendroglioma | Oligodendroglioma | Oligodendrogliomas | Mixed Oligodendroglioma-Astrocytoma | Mixed Oligodendroglioma Astrocytoma | Mixed Oligodendroglioma-Astrocytomas | Oligodendroglioma-Astrocytoma, Mixed | Oligodendroglioma-Astrocytomas, Mixed | Mixed Oligodendroglioma-Ependymoma | Mixed Oligodendroglioma Ependymoma | Mixed Oligodendroglioma-Ependymomas | Oligodendroglioma-Ependymoma, Mixed | Oligodendroglioma-Ependymomas, Mixed | Oligodendroglioma, Adult | Adult Oligodendroglioma | Adult Oligodendrogliomas | Oligodendrogliomas, Adult | Oligodendroglioma, Childhood | Childhood Oligodendroglioma | Childhood Oligodendrogliomas | Oligodendrogliomas, Childhood | Oligodendroglioma, Well-Differentiated | Oligodendroglioma, Well Differentiated | Oligodendrogliomas, Well-Differentiated | Well-Differentiated Oligodendrogliomas | Well-Differentiated Oligodendroglioma | Well Differentiated Oligodendroglioma | Anaplastic Oligodendroglioma | Anaplastic Oligodendrogliomas | Oligodendroglioma, Anaplastic | Oligodendrogliomas, Anaplastic | Oligodendroblastoma | Oligodendroblastomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02150Temozolomide0.000336%
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