Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Juvenile myoclonic epilepsy
ADR ID BADD_A10262
ADR Hierarchy
17      Nervous system disorders
17.12      Seizures (incl subtypes)
17.12.03      Seizures and seizure disorders NEC
17.12.03.037      Juvenile myoclonic epilepsy
Description A disorder characterized by the onset of myoclonus in adolescence, a marked increase in the incidence of absence seizures (see EPILEPSY, ABSENCE), and generalized major motor seizures (see EPILEPSY, TONIC-CLONIC). The myoclonic episodes tend to occur shortly after awakening. Seizures tend to be aggravated by sleep deprivation and alcohol consumption. Hereditary and sporadic forms have been identified. (From Adams et al., Principles of Neurology, 6th ed, p323) [MeSH]
MedDRA Code 10071082
MeSH ID D020190
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Juvenile myoclonic epilepsy | Myoclonic Epilepsy, Juvenile | Epilepsy, Juvenile Myoclonic | Epilepsy, Myoclonic Juvenile | Juvenile Epilepsy, Myoclonic | Myoclonic Juvenile Epilepsy | JME (Juvenile Myoclonic Epilepsy) | JMEs (Juvenile Myoclonic Epilepsy) | Epilepsy, Myoclonic, Juvenile | Juvenile Myoclonic Epilepsy | Juvenile Myoclonic Epilepsy of Janz | Janz Syndrome | Petit Mal, Impulsive, Janz | Janz Juvenile Myoclonic Epilepsy | Impulsive Petit Mal, Janz | Janz Impulsive Petit Mal | Impulsive Petit Mal Epilepsy | Petit Mal, Impulsive | Myoclonic Epilepsy, Juvenile, 1 | Myoclonic Epilepsy, Adolescent | Epilepsy, Adolescent Myoclonic | Adolescent Myoclonic Epilepsy
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01238Lacosamide0.001463%
BADD_D01265Levetiracetam0.000119%
BADD_D02010Sertraline0.000038%
BADD_D02329Valproic acid0.000100%
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