Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Gliosarcoma
ADR ID BADD_A09982
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.30      Nervous system neoplasms malignant and unspecified NEC
16.30.02      Glial tumours malignant
16.30.02.009      Gliosarcoma
17      Nervous system disorders
17.20      Nervous system neoplasms malignant and unspecified NEC
17.20.02      Glial tumours malignant
17.20.02.009      Gliosarcoma
Description Rare mixed tumors of the brain and rarely the spinal cord which contain malignant neuroectodermal (glial) and mesenchymal components, including spindle-shaped fibrosarcoma cells. These tumors are highly aggressive and present primarily in adults as rapidly expanding mass lesions. They may arise in tissue that has been previously irradiated. (From Br J Neurosurg 1995 Apr;9(2):171-8) [MeSH]
MedDRA Code 10018340
MeSH ID D018316
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Gliosarcoma | Gliosarcomas | Glioblastoma with Sarcomatous Component | Sarcomatous Glioma | Glioma, Sarcomatous | Gliomas, Sarcomatous | Sarcomatous Gliomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02150Temozolomide0.000280%
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