Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Extramammary Paget's disease
ADR ID BADD_A09884
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.03      Skin neoplasms malignant and unspecified
16.03.02      Skin neoplasms malignant and unspecified (excl melanoma)
16.03.02.011      Extramammary Paget's disease
23      Skin and subcutaneous tissue disorders
23.08      Skin neoplasms malignant and unspecified
23.08.02      Skin neoplasms malignant and unspecified (excl melanoma)
23.08.02.011      Extramammary Paget's disease
Description A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478) [MeSH]
MedDRA Code 10068223
MeSH ID D010145
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Paget's disease of skin | Extramammary Paget's disease | Paget Disease, Extramammary | Extra-Mammary Paget Disease | Extra Mammary Paget Disease | Extra-Mammary Paget's Disease | Extra Mammary Paget's Disease | Extra-Mammary Pagets Disease | Paget's Disease, Extramammary | Pagets Disease, Extramammary | Extramammary Paget's Disease | Extramammary Pagets Disease | Paget Disease, Extra-Mammary | Paget Disease, Extra Mammary | Paget's Disease, Extra-Mammary | Paget's Disease, Extra Mammary | Pagets Disease, Extra-Mammary | Paget Disease Extramammary | Extramammary, Paget Disease | Extramammary Paget Disease
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00349Capecitabine0.000168%
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