Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Ependymoma
ADR ID BADD_A09867
ADR Hierarchy
17      Nervous system disorders
17.20      Nervous system neoplasms malignant and unspecified NEC
17.20.01      Nervous system neoplasms unspecified malignancy NEC
17.20.01.010      Ependymoma
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.30      Nervous system neoplasms malignant and unspecified NEC
16.30.01      Nervous system neoplasms unspecified malignancy NEC
16.30.01.010      Ependymoma
Description Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9) [MeSH]
MedDRA Code 10014967
MeSH ID D004806
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Ependymoma | Ependymomas | Ependymoma, Papillary | Ependymomas, Papillary | Papillary Ependymomas | Papillary Ependymoma | Ependymoma, Myxopapillary | Ependymomas, Myxopapillary | Myxopapillary Ependymoma | Myxopapillary Ependymomas | Anaplastic Ependymoma | Anaplastic Ependymomas | Ependymoma, Anaplastic | Ependymomas, Anaplastic | Cellular Ependymoma | Clear Cell Ependymoma
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02150Temozolomide0.000112%
BADD_D02192Thalidomide0.000530%
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