Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Embolia cutis medicamentosa
ADR ID BADD_A08377
ADR Hierarchy
24      Vascular disorders
24.01      Embolism and thrombosis
24.01.01      Non-site specific embolism and thrombosis
24.01.01.030      Embolia cutis medicamentosa
08      General disorders and administration site conditions
08.02      Administration site reactions
08.02.03      Injection site reactions
08.02.03.052      Embolia cutis medicamentosa
12      Injury, poisoning and procedural complications
12.07      Administration site reactions
12.07.03      Injection site reactions
12.07.03.052      Embolia cutis medicamentosa
Description An uncommon complication of INTRAMUSCULAR INJECTION leading to variable degrees of necrosis of skin and underlying tissue. [MeSH]
MedDRA Code 10058729
MeSH ID D065148
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Embolia cutis medicamentosa | Nicolau syndrome | Nicolau Syndrome | Syndrome, Nicolau | Livedo-like Dermatitis | Dermatitides, Livedo-like | Dermatitis, Livedo-like | Livedo like Dermatitis | Livedo-like Dermatitides | Nicolau's Livedoid Syndrome | Livedoid Syndrome, Nicolau's | Nicolau Livedoid Syndrome | Nicolaus Livedoid Syndrome | Syndrome, Nicolau's Livedoid | Nicolau's Syndrome | Nicolaus Syndrome | Syndrome, Nicolau's | Embolia Cutis Medicamentosa | Cutis Medicamentosa, Embolia | Medicamentosa, Embolia Cutis | Nicolau Livedoid Dermatitis | Dermatitis, Nicolau Livedoid | Livedoid Dermatitis, Nicolau
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00129Amoxicillin0.000005%
BADD_D00405Ceftriaxone0.004457%
BADD_D00623Dexamethasone0.000145%
BADD_D00653Diclofenac0.001191%
BADD_D00978Fulvestrant0.000501%
BADD_D01710Penicillin g0.069869%
BADD_D01784Piroxicam0.001064%
BADD_D01852Progesterone0.000125%
BADD_D02272Triamcinolone acetonide0.000068%
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