Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Anti-neutrophil cytoplasmic antibody positive vasculitis
ADR ID BADD_A08003
ADR Hierarchy
10      Immune system disorders
10.02      Immune disorders NEC
10.02.02      Vasculitides
10.02.02.023      Anti-neutrophil cytoplasmic antibody positive vasculitis
24      Vascular disorders
24.12      Vascular infections and inflammations
24.12.04      Vasculitides NEC
24.12.04.002      Anti-neutrophil cytoplasmic antibody positive vasculitis
Description Group of systemic vasculitis with a strong association with ANCA. The disorders are characterized by necrotizing inflammation of small and medium size vessels, with little or no immune-complex deposits in vessel walls. [MeSH]
MedDRA Code 10050894
MeSH ID D056648
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Anti-neutrophil cytoplasmic antibody positive vasculitis | De novo ANCA-associated vasculitis | ANCA-associated vasculitis | ANCA associated vasculitis relapse | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Anti Neutrophil Cytoplasmic Antibody Associated Vasculitis | ANCA-Associated Vasculitis | ANCA Associated Vasculitis | Vasculitis, ANCA-Associated | Pauci-Immune Vasculitis | Pauci Immune Vasculitis | Pauci-Immune Vasculitides | Vasculitides, Pauci-Immune | Vasculitis, Pauci-Immune | ANCA-Associated Vasculitides | ANCA Associated Vasculitides | ANCA-Associated Vasculitide | Vasculitide, ANCA-Associated | Vasculitides, ANCA-Associated
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00142Anastrozole0.000159%
BADD_D00800Erlotinib0.000112%
BADD_D01081Hydralazine0.009476%
BADD_D01204Isoniazid0.002780%
BADD_D01213Isotretinoin0.000515%
BADD_D01275Levofloxacin0.000042%
BADD_D01397Mesalamine0.000183%
BADD_D01414Methimazole0.001315%
BADD_D01470Minocycline0.001535%
BADD_D01709Penicillamine0.000103%
BADD_D01834Prednisone0.000009%
BADD_D01869Propylthiouracil0.206889%
BADD_D02093Sulfasalazine0.000455%
BADD_D02105Tacrolimus0.000297%
BADD_D02470Nintedanib0.000224%
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