Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cerebral ventricle dilatation
ADR ID BADD_A07876
ADR Hierarchy
17      Nervous system disorders
17.11      Structural brain disorders
17.11.01      Structural brain disorders NEC
17.11.01.013      Cerebral ventricle dilatation
Description Excessive accumulation of cerebrospinal fluid within the cranium which may be associated with dilation of cerebral ventricles, INTRACRANIAL HYPERTENSION; HEADACHE; lethargy; URINARY INCONTINENCE; and ATAXIA. | Enlargement of CEREBRAL VENTRICLES. Although it is often isolated without other CNS anomalies it can be associated with other congenital malformations (e.g., ARNOLD-CHIARI MALFORMATION; DANDY-WALKER MALFORMATION, and ACROCALLOSAL SYNDROME). [MeSH]
MedDRA Code 10048824
MeSH ID D006849
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cerebral ventricle dilatation | Cerebral ventriculomegaly | Enlargement of optic recess | Hydrocephalus | Hydrocephaly | Cerebral Ventriculomegaly | Cerebral Ventriculomegalies | Ventriculomegalies, Cerebral | Ventriculomegaly, Cerebral | Communicating Hydrocephalus | Hydrocephalus, Communicating | Congenital Hydrocephalus | Hydrocephalus, Congenital | Hydrocephalus Ex-Vacuo | Hydrocephalus Ex Vacuo | Hydrocephalus Ex-Vacuos | Obstructive Hydrocephalus | Hydrocephalus, Obstructive | Post-Traumatic Hydrocephalus | Hydrocephalus, Post-Traumatic | Post Traumatic Hydrocephalus | Aqueductal Stenosis | Aqueductal Stenoses | Stenoses, Aqueductal | Stenosis, Aqueductal | Fetal Cerebral Ventriculomegaly | Cerebral Ventriculomegalies, Fetal | Cerebral Ventriculomegaly, Fetal | Fetal Cerebral Ventriculomegalies | Ventriculomegalies, Fetal Cerebral | Ventriculomegaly, Fetal Cerebral
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00039Acyclovir0.000071%
BADD_D00151Apixaban0.000087%
BADD_D00356Carbamazepine0.000186%
BADD_D00623Dexamethasone0.000145%
BADD_D00749Efavirenz0.007340%
BADD_D00809Escitalopram0.000028%
BADD_D00898Finasteride0.000045%
BADD_D00932Fluoxetine0.000059%
BADD_D01213Isotretinoin0.000257%
BADD_D01243Lamotrigine0.000386%
BADD_D01477Misoprostol0.000925%
BADD_D01679Paroxetine0.000043%
BADD_D01951Risperidone0.000182%
BADD_D01952Ritonavir0.000735%
BADD_D02010Sertraline0.000025%
BADD_D02329Valproic acid0.000549%
BADD_D02373Warfarin0.000042%
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