ADR Ontology |
ADR Term |
Senile dementia |
ADR ID |
BADD_A07688 |
ADR Hierarchy |
|
Description |
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) [MeSH] |
MedDRA Code |
10039966 |
MeSH ID |
D000544
|
ADR Severity Grade (FAERS)
|
|
ADR Severity Grade (CTCAE)
|
Not Available
|
Synonym |
Senile degeneration of brain with dementia | Senile dementia | Senile dementia NOS | Senile dementia with acute confusional state | Senile dementia with delirium | Senile dementia with delusional features | Senile dementia with delusional or depressive features | Senile dementia with depressive features | Senile dementia, depressed or paranoid type | Senile dementia, simple type | Senile dementia, uncomplicated | Senility | Senility without mention of psychosis | Alzheimer Disease | Alzheimer's Disease | Dementia, Senile | Senile Dementia | Dementia, Alzheimer Type | Alzheimer Type Dementia | Alzheimer-Type Dementia (ATD) | Alzheimer Type Dementia (ATD) | Dementia, Alzheimer-Type (ATD) | Alzheimer Type Senile Dementia | Primary Senile Degenerative Dementia | Dementia, Primary Senile Degenerative | Alzheimer Sclerosis | Sclerosis, Alzheimer | Alzheimer Syndrome | Alzheimer Dementia | Alzheimer Dementias | Dementia, Alzheimer | Dementias, Alzheimer | Senile Dementia, Alzheimer Type | Acute Confusional Senile Dementia | Senile Dementia, Acute Confusional | Dementia, Presenile | Presenile Dementia | Alzheimer Disease, Late Onset | Late Onset Alzheimer Disease | Alzheimer's Disease, Focal Onset | Focal Onset Alzheimer's Disease | Familial Alzheimer Disease (FAD) | Alzheimer Disease, Familial (FAD) | Alzheimer Diseases, Familial (FAD) | Familial Alzheimer Diseases (FAD) | Alzheimer Disease, Early Onset | Early Onset Alzheimer Disease | Presenile Alzheimer Dementia |
|
|
Drugs Leading to the ADR |
|