Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Mitral valve stenosis
ADR ID BADD_A07433
ADR Hierarchy
02      Cardiac disorders
02.07      Cardiac valve disorders
02.07.01      Mitral valvular disorders
02.07.01.009      Mitral valve stenosis
Description Narrowing of the passage through the MITRAL VALVE due to FIBROSIS, and CALCINOSIS in the leaflets and chordal areas. This elevates the left atrial pressure which, in turn, raises pulmonary venous and capillary pressure leading to bouts of DYSPNEA and TACHYCARDIA during physical exertion. RHEUMATIC FEVER is its primary cause. [MeSH]
MedDRA Code 10027733
MeSH ID D008946
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Mitral stenosis | Mitral stenosis rheumatic | Mitral valve stenosis | Rheumatic mitral stenosis | Mitral Valve Stenosis | Mitral Valve Stenoses | Stenoses, Mitral Valve | Stenosis, Mitral Valve | Valve Stenoses, Mitral | Valve Stenosis, Mitral | Mitral Stenosis | Mitral Stenoses | Stenoses, Mitral | Stenosis, Mitral
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00151Apixaban0.000174%
BADD_D00285Bosentan0.000120%
BADD_D00405Ceftriaxone0.004457%
BADD_D00932Fluoxetine0.000020%
BADD_D01242Lamivudine0.001012%
BADD_D01567Nilotinib0.000168%
BADD_D01583Norepinephrine0.000085%
BADD_D01679Paroxetine0.000064%
BADD_D01954Rivaroxaban0.000222%
BADD_D02373Warfarin0.000056%
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