Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Medulloblastoma
ADR ID BADD_A07402
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.30      Nervous system neoplasms malignant and unspecified NEC
16.30.02      Glial tumours malignant
16.30.02.006      Medulloblastoma
17      Nervous system disorders
17.20      Nervous system neoplasms malignant and unspecified NEC
17.20.02      Glial tumours malignant
17.20.02.006      Medulloblastoma
Description A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1) [MeSH]
MedDRA Code 10027107
MeSH ID D008527
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Medulloblastoma | Medulloblastomas | Melanocytic Medulloblastoma | Medulloblastoma, Melanocytic | Medulloblastomas, Melanocytic | Melanocytic Medulloblastomas | Medulloblastoma, Childhood | Childhood Medulloblastoma | Childhood Medulloblastomas | Medulloblastomas, Childhood | Medullomyoblastoma | Medullomyoblastomas | Arachnoidal Cerebellar Sarcoma, Circumscribed | Sarcoma, Cerebellar, Circumscribed Arachnoidal | Medulloblastoma, Desmoplastic | Desmoplastic Medulloblastoma | Desmoplastic Medulloblastomas | Medulloblastomas, Desmoplastic | Medulloblastoma, Adult | Adult Medulloblastoma | Adult Medulloblastomas | Medulloblastomas, Adult
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02192Thalidomide0.000241%
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