Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cryoglobulinaemia
ADR ID BADD_A07127
ADR Hierarchy
10      Immune system disorders
10.04      Autoimmune disorders
10.04.04      Autoimmune disorders NEC
10.04.04.013      Cryoglobulinaemia
24      Vascular disorders
24.12      Vascular infections and inflammations
24.12.04      Vasculitides NEC
24.12.04.007      Cryoglobulinaemia
Description A condition characterized by the presence of abnormal quantities of CRYOGLOBULINS in the blood. Upon cold exposure, these abnormal proteins precipitate into the microvasculature leading to restricted blood flow in the exposed areas. [MeSH]
MedDRA Code 10011474
MeSH ID D003449
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cryoglobulinaemia | Cryoglobulinemia | Mixed cryoglobulinemia | Mixed cryoglobulinaemia | Essential mixed cryoglobulinemia | Essential mixed cryoglobulinaemia | Cryoglobulinemic vasculitis | Cryoglobulinaemic vasculitis | Cryoglobulinemias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01119Ibrutinib0.000112%
BADD_D01834Prednisone0.000009%
BADD_D01869Propylthiouracil0.014106%
BADD_D01933Ribavirin0.027691%
BADD_D02053Sofosbuvir0.007056%
BADD_D02105Tacrolimus0.000743%
BADD_D02154Tenofovir0.001939%
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