Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Anal ulcer
ADR ID BADD_A06895
ADR Hierarchy
07      Gastrointestinal disorders
07.04      Gastrointestinal ulceration and perforation
07.04.01      Anal and rectal ulcers and perforation
07.04.01.001      Anal ulcer
Description A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the anal canal. [CTCAE] A painful linear ulcer at the margin of the anus. It appears as a crack or slit in the mucous membrane of the anus and is very painful and difficult to heal. (Dorland, 27th ed & Stedman, 25th ed) [MeSH]
MedDRA Code 10002180
MeSH ID D005401
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Anal ulcer | Solitary ulcer of anus (sphincter) | Stercoral ulcer of anus (sphincter) | Ulcer anal | Ulceration of anus | Perianal ulcer | Fissure in Ano | Anal Fissure | Fissure, Anal | Anal Ulcer | Anal Ulcers | Ulcer, Anal | Ulcers, Anal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00349Capecitabine0.000168%
BADD_D00551Cyclosporine0.000111%
BADD_D01119Ibrutinib0.000112%
BADD_D01285Levothyroxine0.000005%
BADD_D01418Methotrexate0.000114%
BADD_D01653Paclitaxel0.000112%
BADD_D02058Sorafenib0.000168%
BADD_D02100Sunitinib0.000224%
BADD_D02192Thalidomide0.000241%
The 1th Page    1    Total 1 Pages