Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Acoustic neuroma
ADR ID BADD_A06860
ADR Hierarchy
04      Ear and labyrinth disorders
04.04      Inner ear and VIIIth cranial nerve disorders
04.04.04      VIIIth cranial nerve disorders
04.04.04.003      Acoustic neuroma
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.09      Nervous system neoplasms benign
16.09.02      Neuromas
16.09.02.002      Acoustic neuroma
17      Nervous system disorders
17.18      Nervous system neoplasms benign
17.18.02      Neuromas
17.18.02.002      Acoustic neuroma
Description A benign SCHWANNOMA of the eighth cranial nerve (VESTIBULOCOCHLEAR NERVE), mostly arising from the vestibular branch (VESTIBULAR NERVE) during the fifth or sixth decade of life. Clinical manifestations include HEARING LOSS; HEADACHE; VERTIGO; TINNITUS; and FACIAL PAIN. Bilateral acoustic neuromas are associated with NEUROFIBROMATOSIS 2. (From Adams et al., Principles of Neurology, 6th ed, p673) [MeSH]
MedDRA Code 10000523
MeSH ID D009464
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acoustic neurinoma | Acoustic neuroma | Acoustic schwannoma | Vestibular schwannoma | Neuroma, Acoustic | Acoustic Neuroma | Acoustic Neuromas | Neuromas, Acoustic | Schwannoma, Acoustic | Acoustic Schwannoma | Acoustic Schwannomas | Schwannomas, Acoustic | Neurinoma of the Acoustic Nerve | Neurilemoma, Acoustic | Acoustic Neurilemoma | Acoustic Neurilemomas | Neurilemomas, Acoustic | Schwannoma, Vestibular | Schwannomas, Vestibular | Vestibular Schwannomas | Vestibular Schwannoma | Acoustic Tumor | Acoustic Tumors | Tumor, Acoustic | Tumors, Acoustic | Neurilemmoma, Acoustic | Acoustic Neurilemmoma | Acoustic Neurilemmomas | Neurilemmomas, Acoustic | Neurinoma, Acoustic | Acoustic Neurinoma | Acoustic Neurinomas | Neurinomas, Acoustic | Cerebellopontine Angle Acoustic Neuroma | Acoustic Neuroma, Cerebellopontine Angle | Neuroma, Acoustic, Unilateral | Melanocytic Vestibular Schwannoma | Melanocytic Vestibular Schwannomas | Schwannoma, Melanocytic Vestibular | Schwannomas, Melanocytic Vestibular | Vestibular Schwannoma, Melanocytic | Vestibular Schwannomas, Melanocytic | Angle Tumor | Angle Tumors | Tumor, Angle | Tumors, Angle | Cerebellopontine Angle Tumor | Angle Tumor, Cerebellopontine | Angle Tumors, Cerebellopontine | Cerebellopontine Angle Tumors | Tumor, Cerebellopontine Angle | Tumors, Cerebellopontine Angle
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00511Clozapine0.001223%
BADD_D00551Cyclosporine0.000111%
BADD_D00718Doxazosin0.000113%
BADD_D01253Lenalidomide0.000241%
BADD_D02464Fingolimod0.000241%
BADD_D02473Sodium chloride0.000241%
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