Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Bronchioloalveolar carcinoma
ADR ID BADD_A05575
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.19      Respiratory and mediastinal neoplasms malignant and unspecified
16.19.02      Respiratory tract and pleural neoplasms malignant cell type unspecified NEC
16.19.02.002      Bronchioloalveolar carcinoma
22      Respiratory, thoracic and mediastinal disorders
22.08      Respiratory tract neoplasms
22.08.01      Lower respiratory tract neoplasms
22.08.01.003      Bronchioloalveolar carcinoma
Description A carcinoma derived from epithelium of terminal bronchioles, in which the neoplastic tissue extends along the alveolar walls and grows in small masses within the alveoli. Involvement may be uniformly diffuse and massive, or nodular, or lobular. The neoplastic cells are cuboidal or columnar and form papillary structures. Mucin may be demonstrated in some of the cells and in the material in the alveoli, which also includes denuded cells. Metastases in regional lymph nodes, and in even more distant sites, are known to occur, but are infrequent. (From Stedman, 25th ed) [MeSH]
MedDRA Code 10058354
MeSH ID D002282; D018255
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Bronchioalveolar carcinoma | Pulmonary adenomatosis | Alveolar cell carcinoma | Bronchioloalveolar carcinoma | Adenocarcinoma, Bronchiolo-Alveolar | Adenocarcinoma, Bronchiolo Alveolar | Adenocarcinomas, Bronchiolo-Alveolar | Bronchiolo-Alveolar Adenocarcinoma | Bronchiolo-Alveolar Adenocarcinomas | Adenocarcinoma, Alveolar | Adenocarcinomas, Alveolar | Alveolar Adenocarcinoma | Alveolar Adenocarcinomas | Carcinoma, Alveolar | Alveolar Carcinoma | Alveolar Carcinomas | Carcinomas, Alveolar | Carcinoma, Bronchiolo-Alveolar | Bronchiolo-Alveolar Carcinoma | Bronchiolo-Alveolar Carcinomas | Carcinoma, Bronchiolo Alveolar | Carcinomas, Bronchiolo-Alveolar | Alveolar Cell Carcinoma | Alveolar Cell Carcinomas | Carcinoma, Alveolar Cell | Carcinomas, Alveolar Cell | Carcinoma, Bronchiolar | Bronchiolar Carcinoma | Bronchiolar Carcinomas | Carcinomas, Bronchiolar | Carcinoma, Bronchioloalveolar | Bronchioloalveolar Carcinoma | Bronchioloalveolar Carcinomas | Carcinomas, Bronchioloalveolar
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00800Erlotinib0.000112%
BADD_D01253Lenalidomide--
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