Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Chronic hepatic failure
ADR ID BADD_A05507
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.03      Hepatic failure and associated disorders
09.01.03.009      Chronic hepatic failure
Description Final stage of a liver disease when the liver failure is irreversible and LIVER TRANSPLANTATION is needed. [MeSH]
MedDRA Code 10057573
MeSH ID D058625
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
End stage liver disease | Chronic hepatic failure | End Stage Liver Disease | Chronic Liver Failure | Chronic Liver Failures | Failure, Chronic Liver | Failures, Chronic Liver | Liver Failures, Chronic | Liver Failure, Chronic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00100Ambrisentan0.000241%
BADD_D00858Everolimus--
BADD_D01213Isotretinoin0.000257%
BADD_D01336Macitentan0.000120%
BADD_D01592Obeticholic acid0.001564%
BADD_D01933Ribavirin0.003956%
BADD_D01938Rifaximin0.001929%
BADD_D01954Rivaroxaban0.000063%
BADD_D02053Sofosbuvir0.000282%
BADD_D02154Tenofovir0.001939%
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