Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Dacryostenosis acquired
ADR ID BADD_A05312
ADR Hierarchy
06      Eye disorders
06.06      Anterior eye structural change, deposit and degeneration
06.06.04      Lid, lash and lacrimal structural disorders
06.06.04.003      Dacryostenosis acquired
Description Interference with the secretion of tears by the lacrimal glands. Obstruction of the LACRIMAL SAC or NASOLACRIMAL DUCT causing acute or chronic inflammation of the lacrimal sac (DACRYOCYSTITIS). It is caused also in infants by failure of the nasolacrimal duct to open into the inferior meatus and occurs about the third week of life. In adults occlusion may occur spontaneously or after injury or nasal disease. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p250) [MeSH]
MedDRA Code 10053990
MeSH ID D007767
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Blocked tear duct (excl congenital) | Lacrimal duct obstruction | Lacrimal duct obstruction (acquired) | Lacrimal duct obstruction NOS | Stenosis and insufficiency of lacrimal passages | Stenosis of lacrimal canaliculi | Stenosis of lacrimal punctum | Stenosis of lacrimal sac | Stenosis of nasolacrimal duct, acquired | Dacryostenosis acquired | Lacrimal Duct Obstruction | Duct Obstruction, Lacrimal | Duct Obstructions, Lacrimal | Lacrimal Duct Obstructions | Obstruction, Lacrimal Duct | Obstructions, Lacrimal Duct | Tear Duct Obstruction | Duct Obstruction, Tear | Duct Obstructions, Tear | Obstruction, Tear Duct | Obstructions, Tear Duct | Tear Duct Obstructions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00274Bimatoprost0.000598%
BADD_D00349Capecitabine0.000168%
BADD_D00551Cyclosporine0.000376%
BADD_D00623Dexamethasone0.000218%
BADD_D00699Docetaxel--
BADD_D00908Floxuridine--
BADD_D01119Ibrutinib0.000302%
BADD_D01253Lenalidomide0.001640%
BADD_D01290Lifitegrast0.004087%
BADD_D01324Loteprednol etabonate0.002061%
BADD_D01418Methotrexate--
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01954Rivaroxaban0.000095%
BADD_D02113Tamsulosin0.000019%
BADD_D02236Tofacitinib0.000651%
BADD_D02519Netarsudil0.002192%
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