Adverse Drug Reaction Classification System

ADR Ontology
ADR Term HELLP syndrome
ADR ID BADD_A04787
ADR Hierarchy
24      Vascular disorders
24.08      Vascular hypertensive disorders
24.08.07      Pregnancy associated hypertension
24.08.07.005      HELLP syndrome
18      Pregnancy, puerperium and perinatal conditions
18.02      Maternal complications of pregnancy
18.02.03      Hypertension associated disorders of pregnancy
18.02.03.005      HELLP syndrome
01      Blood and lymphatic system disorders
01.08      Platelet disorders
01.08.01      Thrombocytopenias
01.08.01.008      HELLP syndrome
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.02      Hepatic enzymes and function abnormalities
09.01.02.006      HELLP syndrome
Description A syndrome of HEMOLYSIS, elevated liver ENZYMES, and low blood platelets count (THROMBOCYTOPENIA). HELLP syndrome is observed in pregnant women with PRE-ECLAMPSIA or ECLAMPSIA who also exhibit LIVER damage and abnormalities in BLOOD COAGULATION. [MeSH]
MedDRA Code 10049058
MeSH ID D017359
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
HELLP syndrome | HELLP Syndrome | Syndrome, HELLP | Hemolysis, Elevated Liver Enzymes, Lowered Platelets
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00932Fluoxetine0.000030%
BADD_D01160Insulin aspart--
BADD_D01236Labetalol0.000488%
BADD_D01281Levonorgestrel0.000473%
BADD_D01425Methyldopa0.001027%
BADD_D01477Misoprostol0.000617%
BADD_D01566Nifedipine0.000112%
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