Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Enzyme induction
ADR ID BADD_A04711
ADR Hierarchy
14      Metabolism and nutrition disorders
14.11      Metabolism disorders NEC
14.11.01      Metabolic disorders NEC
14.11.01.022      Enzyme induction
08      General disorders and administration site conditions
08.06      Therapeutic and nontherapeutic effects (excl toxicity)
08.06.01      Therapeutic and nontherapeutic responses
08.06.01.022      Enzyme induction
Description An increase in the rate of synthesis of an enzyme due to the presence of an inducer which acts to derepress the gene responsible for enzyme synthesis. [MeSH]
MedDRA Code 10048652
MeSH ID D004790
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Enzyme induction | Acetylation increased | Enzyme Induction | Induction, Enzyme
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00356Carbamazepine--
BADD_D00749Efavirenz--
BADD_D02011Sertraline hydrochloride--
BADD_D02329Valproic acid--
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