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ADR Ontology
ADR Term
Enzyme induction
ADR ID
BADD_A04711
ADR Hierarchy
14
Metabolism and nutrition disorders
14.11
Metabolism disorders NEC
14.11.01
Metabolic disorders NEC
14.11.01.022
Enzyme induction
08
General disorders and administration site conditions
08.06
Therapeutic and nontherapeutic effects (excl toxicity)
08.06.01
Therapeutic and nontherapeutic responses
08.06.01.022
Enzyme induction
Description
An increase in the rate of synthesis of an enzyme due to the presence of an inducer which acts to derepress the gene responsible for enzyme synthesis. [MeSH]
MedDRA Code
10048652
MeSH ID
D004790
ADR Severity Grade (FAERS)
Not Available
ADR Severity Grade (CTCAE)
Not Available
Synonym
Enzyme induction | Acetylation increased | Enzyme Induction | Induction, Enzyme
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00356
Carbamazepine
-
-
BADD_D00749
Efavirenz
-
-
BADD_D02011
Sertraline hydrochloride
-
-
BADD_D02329
Valproic acid
-
-
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