Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Rhabdomyolysis
ADR ID BADD_A03877
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.05      Myopathies
15.05.05.002      Rhabdomyolysis
Description A disorder characterized by the breakdown of muscle tissue resulting in the release of muscle fiber contents into the bloodstream. [CTCAE] Necrosis or disintegration of skeletal muscle often followed by myoglobinuria. [MeSH]
MedDRA Code 10039020
MeSH ID D012206
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Muscle dissolution | Rhabdomyolysis | Rhabdomyolyses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01240Lactulose0.000805%
BADD_D01241Lamisil--
BADD_D01242Lamivudine0.003036%
BADD_D01243Lamotrigine0.001104%
BADD_D01245Lansoprazole0.000398%
BADD_D01253Lenalidomide--
BADD_D01265Levetiracetam0.011885%
BADD_D01271Levocarnitine0.008625%
BADD_D01275Levofloxacin0.000430%
BADD_D01285Levothyroxine0.000027%
BADD_D01295Linezolid0.019759%
BADD_D01303Lithium carbonate0.000803%
BADD_D01304Lithium cation0.000384%
BADD_D01317Loratadine0.000032%
BADD_D01318Lorazepam0.000431%
BADD_D01322Losartan0.000069%
BADD_D01323Losartan potassium--
BADD_D01325Lovastatin0.000042%
BADD_D01328Lubiprostone0.000852%
BADD_D01330Lurasidone0.000820%
BADD_D01331Lurasidone hydrochloride--
BADD_D01352Maraviroc--
BADD_D01374Meloxicam0.000079%
BADD_D01376Melphalan--
BADD_D01378Memantine0.000363%
BADD_D01393Meropenem0.000097%
BADD_D01401Metformin0.000208%
BADD_D01405Methadone0.007425%
BADD_D01414Methimazole0.000708%
BADD_D01432Methylphenidate hydrochloride--
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ADReCS-Target
ADR Term Drug Name Target