ADR Ontology |
ADR Term |
Poliomyelitis |
ADR ID |
BADD_A03488 |
ADR Hierarchy |
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Description |
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5) [MeSH] |
MedDRA Code |
10036012 |
MeSH ID |
D011051
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ADR Severity Grade (FAERS)
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Not Available
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ADR Severity Grade (CTCAE)
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Not Available
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Synonym |
Acute anterior poliomyelitis | Acute nonparalytic poliomyelitis | Acute nonparalytic poliomyelitis, poliovirus type i | Acute nonparalytic poliomyelitis, poliovirus type ii | Acute nonparalytic poliomyelitis, poliovirus type iii | Acute nonparalytic poliomyelitis, unspecified type poliovirus | Acute poliomyelitis | Acute poliomyelitis with other paralysis | Acute poliomyelitis with other paralysis, poliovirus type i | Acute poliomyelitis with other paralysis, poliovirus type ii | Acute poliomyelitis with other paralysis, poliovirus type iii | Acute poliomyelitis with other paralysis, unspecified type of poliovirus | Acute poliomyelitis, unspecified | Acute poliomyelitis, unspecified, poliovirus type i | Acute poliomyelitis, unspecified, poliovirus type ii | Acute poliomyelitis, unspecified, poliovirus type iii | Acute poliomyelitis, unspecified, poliovirus, unspecified type | Acute unspecified poliomyelitis | Polio | Polio acute | Polio-like paralysis | Poliomyelitis | Poliomyelitis (acute) | Poliomyelitis acute | Poliomyelitis NOS | Acute non-paralytic poliomyelitis | Acute non-paralytic poliomyelitis, poliovirus type I | Acute non-paralytic poliomyelitis, poliovirus type II | Acute non-paralytic poliomyelitis, poliovirus type III | Acute non-paralytic poliomyelitis, unspecified type poliovirus | Heine-Medin disease | Poliomyelitis, Acute | Acute Poliomyelitis | Epidemic Acute Poliomyelitis | Acute Poliomyelitis, Epidemic | Poliomyelitis, Epidemic Acute | Poliomyelitis Infection | Infection, Poliomyelitis | Infections, Poliomyelitis | Poliomyelitis Infections | Polios | Poliomyelitis, Preparalytic | Poliomyelitides, Preparalytic | Preparalytic Poliomyelitis | Poliomyelitis, Nonpoliovirus | Nonpoliovirus Poliomyelitis | Encephalitis, Polio | Polio Encephalitis | Infantile Paralysis | Paralysis, Infantile |
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Drugs Leading to the ADR |
Drug ID | Drug Name | ADR Frequency (FAERS) | ADR Severity Grade (FAERS) | BADD_D01966 | Ropinirole | - | - | BADD_D01989 | Saquinavir mesylate | - | - |
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