Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Peripheral coldness
ADR ID BADD_A03365
ADR Hierarchy
23      Skin and subcutaneous tissue disorders
23.06      Skin vascular abnormalities
23.06.04      Skin vascular conditions NEC
23.06.04.008      Peripheral coldness
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.09      Feelings and sensations NEC
08.01.09.010      Peripheral coldness
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.03      Peripheral vasoconstriction, necrosis and vascular insufficiency
24.04.03.006      Peripheral coldness
Description Not Available
MedDRA Code 10034568
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cold extremities | Cold feet | Cold hands | Cold hands & feet | Coldness of limbs | Coldness of lower extremities | Coldness of skin | Fingers cold feeling of | Peripheral coldness
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02220Timolol maleate--
BADD_D02236Tofacitinib0.007860%
BADD_D02247Topiramate--
BADD_D02254Tramadol0.000029%
BADD_D02331Valsartan0.000116%
BADD_D02344Vemurafenib0.000112%
BADD_D02346Venlafaxine0.000071%
BADD_D02348Verapamil0.000099%
BADD_D02355Vigabatrin0.000336%
BADD_D02362Vinflunine--
BADD_D02364Vinorelbine tartrate--
BADD_D02373Warfarin0.000070%
BADD_D02378Zalcitabine--
BADD_D02392Zoledronic acid0.012024%
BADD_D02407Upadacitinib--
BADD_D02412Octreotide--
BADD_D02436Atorvastatin--
BADD_D02440Lisdexamfetamine0.000779%
BADD_D02457Dexmethylphenidate0.000375%
BADD_D02464Fingolimod0.003496%
BADD_D02470Nintedanib0.000112%
BADD_D02473Sodium chloride0.000241%
BADD_D02483Ribociclib0.000112%
BADD_D02490Apalutamide0.000334%
BADD_D02510Rucaparib0.000302%
BADD_D02511Siponimod0.000530%
BADD_D02558Gadolinium cation (3+)-
BADD_D02565Lumateperone0.000666%
BADD_D02603Tucatinib0.000381%
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