Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Paraparesis
ADR ID BADD_A03299
ADR Hierarchy
17      Nervous system disorders
17.01      Movement disorders (incl parkinsonism)
17.01.04      Paralysis and paresis (excl cranial nerve)
17.01.04.006      Paraparesis
Description Mild to moderate loss of bilateral lower extremity motor function, which may be a manifestation of SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; MUSCULAR DISEASES; INTRACRANIAL HYPERTENSION; parasagittal brain lesions; and other conditions. [MeSH]
MedDRA Code 10033885
MeSH ID D020335; D020336
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Paraparesis | Progressive paraparesis chronic | Bilateral leg paresis | Spastic paraparesis | Flaccid paraparesis | Ataxic paraparesis | Parapareses | Paraparesis, Spinal | Spinal Paraparesis | Paraparesis, Hypotonic | Hypotonic Paraparesis | Paraparesis, Cerebral | Cerebral Paraparesis | Paraparesis, Chronic Progressive | Chronic Progressive Paraparesis | Progressive Paraparesis, Chronic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02373Warfarin0.000028%
BADD_D02423Fondaparinux0.004934%
BADD_D02464Fingolimod0.004461%
BADD_D02511Siponimod0.000603%
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