Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Neurofibromatosis
ADR ID BADD_A03042
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.09      Nervous system neoplasms benign
16.09.01      Nervous system neoplasms benign NEC
16.09.01.002      Neurofibromatosis
03      Congenital, familial and genetic disorders
03.10      Neurological disorders congenital
03.10.01      Neurological disorders congenital NEC
03.10.01.002      Neurofibromatosis
17      Nervous system disorders
17.18      Nervous system neoplasms benign
17.18.01      Nervous system neoplasms benign NEC
17.18.01.002      Neurofibromatosis
23      Skin and subcutaneous tissue disorders
23.05      Pigmentation disorders
23.05.01      Hyperpigmentation disorders
23.05.01.018      Neurofibromatosis
Description A group of disorders characterized by an autosomal dominant pattern of inheritance with high rates of spontaneous mutation and multiple neurofibromas or neurilemmomas. NEUROFIBROMATOSIS 1 (generalized neurofibromatosis) accounts for approximately 95% of cases, although multiple additional subtypes (e.g., NEUROFIBROMATOSIS 2, neurofibromatosis 3, etc.) have been described. (From Neurochirurgie 1998 Nov;44(4):267-72) [MeSH]
MedDRA Code 10029268
MeSH ID D017253
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Neurofibromatosis | Neurofibromatosis aggravated | Neurofibromatosis, type 1 (von Recklinghausen's disease) | Neurofibromatosis, type 2 (acoustic neurofibromatosis) | Neurofibromatosis, unspecified | Von Recklinghausen's disease (of nerve) | Neurofibromatosis type 6 | Neurofibromatoses | Neurofibromatosis Syndrome | Neurofibromatosis Syndromes | Syndrome, Neurofibromatosis | Syndromes, Neurofibromatosis | Multiple Neurofibromas | Multiple Neurofibroma | Neurofibroma, Multiple | Neurofibromas, Multiple | Neurofibromatosis 3 | Neurofibromatosis 3s | Neurofibromatosis Type 3 | Neurofibromatosis Type 3s | Type 3, Neurofibromatosis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
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