Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Nephrosclerosis
ADR ID BADD_A03026
ADR Hierarchy
20      Renal and urinary disorders
20.05      Nephropathies
20.05.03      Nephropathies and tubular disorders NEC
20.05.03.007      Nephrosclerosis
Description Hardening of the KIDNEY due to infiltration by fibrous connective tissue (FIBROSIS), usually caused by renovascular diseases or chronic HYPERTENSION. Nephrosclerosis leads to renal ISCHEMIA. [MeSH]
MedDRA Code 10029159
MeSH ID D009400
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Nephrosclerosis | Nephrosclerosis arteriolar | Renal sclerosis | Renal sclerosis, unspecified | Nephroscleroses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00551Cyclosporine0.000221%
BADD_D00858Everolimus--
BADD_D01119Ibrutinib0.000112%
BADD_D01245Lansoprazole0.000099%
BADD_D01250Lasofoxifene--
BADD_D01533Naproxen--
BADD_D02026Simvastatin0.000016%
BADD_D02105Tacrolimus0.000446%
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