Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Muscle spasms
ADR ID BADD_A02889
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.03      Muscle related signs and symptoms NEC
15.05.03.004      Muscle spasms
Description A sustained and usually painful contraction of muscle fibers. This may occur as an isolated phenomenon or as a manifestation of an underlying disease process (e.g., UREMIA; HYPOTHYROIDISM; MOTOR NEURON DISEASE; etc.). (From Adams et al., Principles of Neurology, 6th ed, p1398) [MeSH]
MedDRA Code 10028334
MeSH ID D009120; D013035; D013746
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cramp | Cramp in hand | Cramp in legs thighs | Cramp legs | Cramp muscle | Cramp of limb | Cramps | Cramps calf | Cramps in legs | Cramps in the calves | Cramps leg | Cramps legs | Cramps of lower body | Cramps of lower extremities | Foot cramps | Generalized spasm | Leg cramps | Muscle cramp | Muscle cramps | Muscle cramps aggravated | Muscle spasm | Muscle spasms | Muscular spasm | Neck cramps | Night cramps | Nocturnal leg muscle cramps | Spasm generalised | Spasm generalized | Spasm muscle | Spasm of muscle | Spasms | Tetanic spasm generalized | Cervical spasm | Finger cramps | Systremma | Spasmophilia | Charley horse | Back muscle spasms | Generalised spasm | Tetanic spasm generalised | Cramps of upper extremities | Cramps of extremities | Toe cramps | Leg spasm | Muscle Cramp | Cramp, Muscle | Cramps, Muscle | Muscle Cramps | Muscular Cramp | Cramp, Muscular | Cramps, Muscular | Muscular Cramps | Limb Cramp | Cramp, Limb | Cramps, Limb | Limb Cramps
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02463Pitavastatin0.014425%
BADD_D02464Fingolimod0.057843%
BADD_D02466Levomilnacipran0.000137%
BADD_D02467Naloxegol0.022613%
BADD_D02470Nintedanib--
BADD_D02472Sonidegib0.002642%
BADD_D02473Sodium chloride--
BADD_D02482Acalabrutinib--
BADD_D02489Neratinib0.003492%
BADD_D02495Duvelisib0.000437%
BADD_D02496Elagolix0.003260%
BADD_D02497Avatrombopag0.001555%
BADD_D02509Brigatinib0.001298%
BADD_D02510Rucaparib0.004421%
BADD_D02511Siponimod--
BADD_D02514Etelcalcetide0.049730%
BADD_D02515Pexidartinib0.000302%
BADD_D02521Sodium zirconium cyclosilicate0.006319%
BADD_D02524Ivosidenib0.001198%
BADD_D02526Larotrectinib0.000492%
BADD_D02528Asciminib0.000246%
BADD_D02533Bempedoic acid0.000338%
BADD_D02539Calcium0.001644%
BADD_D02548Darolutamide0.001468%
BADD_D02550Diroximel fumarate0.003400%
BADD_D02551Docusate--
BADD_D02557Finerenone0.000326%
BADD_D02561Isavuconazole0.000150%
BADD_D02569Magnesium0.002825%
BADD_D02576Opicapone0.000807%
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