Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Limb reduction defect
ADR ID BADD_A02536
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.11      Musculoskeletal and connective tissue disorders congenital
03.11.07      Musculoskeletal and connective tissue disorders of limbs congenital
03.11.07.004      Limb reduction defect
15      Musculoskeletal and connective tissue disorders
15.11      Musculoskeletal and connective tissue disorders congenital
15.11.07      Musculoskeletal and connective tissue disorders of limbs congenital
15.11.07.004      Limb reduction defect
Description Gross hypo- or aplasia of one or more long bones of one or more limbs. The concept includes amelia, hemimelia, phocomelia, and sirenomelia. [MeSH]
MedDRA Code 10024503
MeSH ID D004480
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Absence of limbs | Absent limb | Absent limbs | Amelia | Congenital hand agenesis | Ectromelia | Ectromelia four limbs | Ectromelia one limb | Ectromelia three limbs | Ectromelia two limbs | Hemimelia | Limb reduction defect | Limb reduction deformity | Longitudinal def, tarsals or metatarsals, complete or partial (with or w/o incomp phalangeal def) | Longitudinal deficiency of lower limb, not elsewhere classified | Longitudinal deficiency of upper limb, not elsewhere classified | Longitudinal deficiency, carp or metacarp, complete or partial (with or w/o incomp phalangeal def) | Longitudinal deficiency, combined, involving femur, tibia, and fibula (complete or incomplete) | Longitudinal deficiency, combined, involving humerus, radius, and ulna (complete or incomplete) | Longitudinal deficiency, femoral, complete or partial (with or w/o distal deficiencies, incomplete) | Longitudinal deficiency, fibular, complete or partial (with or w/o distal deficiencies, incomplete) | Longitudinal deficiency, humeral, complete or partial (with or w/o distal deficiencies, incomplete) | Longitudinal deficiency, phalanges of foot, complete or partial (with or w/o distal def, incomplete) | Longitudinal deficiency, phalanges of hand, complete or partial (with or w/o distal def, incomplete) | Longitudinal deficiency, radial, complete or partial (with or w/o distal deficiencies, incomplete) | Longitudinal deficiency, radioulnar, complete or partial (with or w/o distal deficiencies, incomp) | Longitudinal deficiency, tibia, complete or partial (with or w/o distal deficiencies, incomplete) | Longitudinal deficiency, tibiofibular, complete or partial (with or w/o distal deficiencies, incomp) | Longitudinal deficiency, ulnar, complete or partial (with or w/o distal deficiencies, incomplete) | Mesomelia | Micromelia | Phocomelia | Reduction deformities of lower limb, congenital | Reduction deformities of upper limb, congenital | Reduction deformities, unspecified limb, congenital | Transverse deficiency of lower limb | Transverse deficiency of upper limb | Unspecified reduction deformity of lower limb, congenital | Unspecified reduction deformity of upper limb, congenital | Foot agenesis | Brachymelia | Acheiropody | Acheiria | Meromelia | Sirenomelia | Mermaid Malformation | Malformation, Mermaid | Sirenomelus | Sirenomelia Sequence | Sequence, Sirenomelia | Sirenomelia Sequences | Fused Legs and Feet | Mermaid Syndrome | Syndrome, Mermaid
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00497Clomiphene--
BADD_D02192Thalidomide--
BADD_D02355Vigabatrin--
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