Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Jaundice cholestatic
ADR ID BADD_A02423
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.01      Cholestasis and jaundice
09.01.01.005      Jaundice cholestatic
Description Jaundice, the condition with yellowish staining of the skin and mucous membranes, that is due to impaired BILE flow in the BILIARY TRACT, such as INTRAHEPATIC CHOLESTASIS, or EXTRAHEPATIC CHOLESTASIS. [MeSH]
MedDRA Code 10023129
MeSH ID D041781
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cholestatic jaundice | Jaundice cholestatic | Jaundice extrahepatic obstructive | Jaundice extrahepatic obstructive NOS | Obstructive jaundice | Jaundice extrahepatic | Cholestatic icterus | Mechanical jaundice | Jaundice, Obstructive | Obstructive Jaundice | Jaundice, Mechanical | Mechanical Jaundice | Jaundice, Cholestatic | Cholestatic Jaundice
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02266Trazodone--
BADD_D02276Triamterene hydrochlorothiazide--
BADD_D02281Trifluoperazine--
BADD_D02286Trimeprazine tartrate--
BADD_D02290Trimethoprim--
BADD_D02345Venetoclax0.000168%
BADD_D02369Voriconazole0.008713%
BADD_D02389Ziprasidone hydrochloride--
BADD_D02391Ziprasidone mesylate--
BADD_D02392Zoledronic acid0.005726%
BADD_D02396Zonisamide--
BADD_D02470Nintedanib0.000168%
BADD_D02480Alectinib0.000112%
BADD_D02504Lorlatinib0.000224%
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