Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hyperacusis
ADR ID BADD_A02104
ADR Hierarchy
04      Ear and labyrinth disorders
04.02      Hearing disorders
04.02.02      Hyperacusia
04.02.02.001      Hyperacusis
17      Nervous system disorders
17.04      Cranial nerve disorders (excl neoplasms)
17.04.03      Facial cranial nerve disorders
17.04.03.003      Hyperacusis
Description An abnormally disproportionate increase in the sensation of loudness in response to auditory stimuli of normal volume. COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; FACIAL NERVE DISEASES; STAPES SURGERY; and other disorders may be associated with this condition. [MeSH]
MedDRA Code 10020559
MeSH ID D012001
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Auditory hyperacuity | Hearing abnormally acute | Hyperacusis | Painful sensitiveness to sound | Sound sensitivity increased | Hyperacuses | Loudness Recruitment | Loudness Recruitments | Hyperacusia | Hyperacusias | Loudness Perception Disturbances | Disturbance, Loudness Perception | Disturbances, Loudness Perception | Loudness Perception Disturbance | Perception Disturbance, Loudness | Perception Disturbances, Loudness | Recruitment, Loudness | Phonophobia | Phonophobias | Auditory Hyperesthesia | Auditory Hyperesthesias | Hyperesthesia, Auditory | Hyperesthesias, Auditory
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00989Gadolinium--
BADD_D00994Gadoversetamide--
BADD_D01119Ibrutinib0.000112%
BADD_D01167Interferon alfa-2b--
BADD_D01243Lamotrigine0.000110%
BADD_D01265Levetiracetam0.000238%
BADD_D01281Levonorgestrel0.002458%
BADD_D01285Levothyroxine0.000031%
BADD_D01287Lidocaine--
BADD_D01290Lifitegrast0.000881%
BADD_D01321Lormetazepam--
BADD_D01366Medroxyprogesterone acetate--
BADD_D01374Meloxicam--
BADD_D01431Methylphenidate0.000090%
BADD_D01470Minocycline--
BADD_D01476Mirtazapine--
BADD_D01484Modafinil--
BADD_D01496Montelukast0.000015%
BADD_D01501Moxifloxacin--
BADD_D01502Moxifloxacin hydrochloride--
BADD_D01546Nefazodone--
BADD_D01547Nefazodone hydrochloride--
BADD_D01579Nitroglycerin0.000097%
BADD_D01588Nortriptyline--
BADD_D01598Ofloxacin0.000167%
BADD_D01621Optimark--
BADD_D01679Paroxetine0.000043%
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
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