Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Graft versus host disease
ADR ID BADD_A01874
ADR Hierarchy
10      Immune system disorders
10.02      Immune disorders NEC
10.02.01      Immune and associated conditions NEC
10.02.01.027      Graft versus host disease
12      Injury, poisoning and procedural complications
12.02      Procedural related injuries and complications NEC
12.02.09      Transplantation complications
12.02.09.001      Graft versus host disease
Description The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION. [MeSH]
MedDRA Code 10018651
MeSH ID D006086
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Graft versus host disease | Graft versus host reaction | Graft-versus-host disease | GVH disease | GVHD | Autologous graft versus host disease | Graft vs Host Disease | Graft-Versus-Host Disease | Disease, Graft-Versus-Host | Diseases, Graft-Versus-Host | Graft Versus Host Disease | Graft-Versus-Host Diseases | Runt Disease | Disease, Runt | Graft-vs-Host Disease | Disease, Graft-vs-Host | Diseases, Graft-vs-Host | Graft-vs-Host Diseases | Homologous Wasting Disease | Disease, Homologous Wasting
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02028Sirolimus0.001233%
BADD_D02105Tacrolimus0.007872%
BADD_D02192Thalidomide0.000241%
BADD_D02203Thiotepa0.001007%
BADD_D02369Voriconazole0.017426%
BADD_D02453Midostaurin0.000224%
BADD_D02502Letermovir0.001129%
BADD_D02505Gilteritinib0.000728%
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