| ADR Ontology |
| ADR Term |
Glomerulonephritis membranoproliferative |
| ADR ID |
BADD_A01849 |
| ADR Hierarchy |
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| Description |
Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN. | A type of mesangiocapillary glomerulonephritis that is characterized by subepithelial immune deposit and may be a variant of type I. | A type of mesangiocapillary glomerulonephritis that is characterized by immune deposits on the endothelial side of the GLOMERULAR BASEMENT MEMBRANE leading to splitting and reduplication of the basement membrane. | A type of mesangiocapillary glomerulonephritis that is characterized by the dark bands of electron-dense deposits in the GLOMERULAR BASEMENT MEMBRANE caused by autoantibodies against ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb). [MeSH] |
| MedDRA Code |
10018370 |
| MeSH ID |
D015432
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Glomerulonephritis membranoproliferative | Glomerulonephritis membranoproliferative acute | Membranoproliferative glomerulonephritis | Mesangiocapillary glomerulonephritis | Nephritis and nephropathy, not specified as acute or chronic, with lesion of membranoprolif glomneph | Glomerulonephritis, Membranoproliferative | Glomerulonephritides, Membranoproliferative | Membranoproliferative Glomerulonephritides | Glomerulonephritis, Mesangiocapillary | Glomerulonephritides, Mesangiocapillary | Mesangiocapillary Glomerulonephritides | MPGN | Membranoproliferative Glomerulonephritis | Mesangiocapillary Glomerulonephritis | Glomerulonephritis, Hypocomplementemic | Glomerulonephritides, Hypocomplementemic | Hypocomplementemic Glomerulonephritides | Hypocomplementemic Glomerulonephritis | Membranoproliferative Glomerulonephritis, Type III | Membranoproliferative Glomerulonephritis, Type I | Subendothelial Membranoproliferative Glomerulonephritis | Membranoproliferative Glomerulonephritis, Subendothelial | Mesangiocapillary Glomerulonephritis, Type I | Membranoproliferative Glomerulonephritis, Type II | Dense Deposit Disease | Type II MPGN | Mesangiocapillary Glomerulonephritis, Type II | MPGNII | DDD MPGNII | Membranoproliferative Glomerulonephritis Type II |
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| Drugs Leading to the ADR |
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