Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Gastrooesophageal reflux disease
ADR ID BADD_A01741
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.003      Gastrooesophageal reflux disease
Description Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER. [MeSH]
MedDRA Code 10017885
MeSH ID D005764; D004942
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acid reflux (oesophageal) | Esophageal reflux | Gastrooesophageal reflux | Gastrooesophageal reflux disease | Gastroesophageal reflux | GERD | Oesophageal reflux | Oesophageal reflux aggravated | Reflux esophagitis | Reflux oesophagitis | Esophageal reflux aggravated | Esophageal acid reflux | Acid reflux (esophageal) | Oesophageal acid reflux | Gastroesophageal reflux disease | Non-erosive reflux disease | Endoscopy negative reflux disease | GORD | Gastroesophageal Reflux | Gastric Acid Reflux | Acid Reflux, Gastric | Reflux, Gastric Acid | Gastric Acid Reflux Disease | Gastro-Esophageal Reflux | Gastro Esophageal Reflux | Reflux, Gastro-Esophageal | Gastroesophageal Reflux Disease | Reflux, Gastroesophageal | Esophageal Reflux | Gastro-oesophageal Reflux | Gastro oesophageal Reflux | Reflux, Gastro-oesophageal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01120Ibuprofen--
BADD_D01121Ibuprofen lysine--
BADD_D01126Icosapent ethyl-
BADD_D01130Idelalisib--
BADD_D01132Idursulfase--
BADD_D01134Iloperidone--
BADD_D01136Imatinib0.002250%
BADD_D01137Imatinib mesylate--
BADD_D01142Imiquimod--
BADD_D01162Insulin detemir--
BADD_D01191Ipratropium0.000138%
BADD_D01194Irbesartan--
BADD_D01197Iron--
BADD_D01213Isotretinoin0.007642%
BADD_D01218Ivabradine0.000085%
BADD_D01222Ixabepilone--
BADD_D01244Lanreotide acetate--
BADD_D01245Lansoprazole0.002397%
BADD_D01248Lapatinib0.001198%
BADD_D01253Lenalidomide--
BADD_D01254Lenvatinib--
BADD_D01256Lesinurad--
BADD_D01258Leucovorin0.003098%
BADD_D01262Levalbuterol--
BADD_D01275Levofloxacin--
BADD_D01285Levothyroxine0.000109%
BADD_D01290Lifitegrast0.006130%
BADD_D01291Linaclotide--
BADD_D01292Linagliptin0.000946%
BADD_D01298Liraglutide--
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