Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Gastrinoma
ADR ID BADD_A01735
ADR Hierarchy
05      Endocrine disorders
05.08      Neoplastic and ectopic endocrinopathies
05.08.01      Endocrine neoplasms NEC
05.08.01.003      Gastrinoma
07      Gastrointestinal disorders
07.21      Malignant and unspecified neoplasms gastrointestinal NEC
07.21.04      Gastrointestinal neoplasms NEC
07.21.04.007      Gastrinoma
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.24      Endocrine neoplasms malignant and unspecified
16.24.02      Islet cell neoplasms and APUDoma NEC
16.24.02.002      Gastrinoma
Description A GASTRIN-secreting neuroendocrine tumor of the non-beta ISLET CELLS, the GASTRIN-SECRETING CELLS. This type of tumor is primarily located in the PANCREAS or the DUODENUM. Majority of gastrinomas are malignant. They metastasize to the LIVER; LYMPH NODES; and BONE but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN 1). [MeSH]
MedDRA Code 10017852
MeSH ID D015408; D015043
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Gastrinoma | Syndrome Zollinger Ellison | Z-E syndrome | Zollinger-Ellison syndrome | Gastrinomas | Islet Cell Tumor, Ulcerogenic | Ulcerogenic Islet Cell Tumor | Gastrin-Producing Tumor | Gastrin Producing Tumor | Gastrin-Producing Tumors | Tumor, Gastrin-Producing | Tumors, Gastrin-Producing
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01614Omeprazole--
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