Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Essential thrombocythaemia
ADR ID BADD_A01552
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.21      Haematopoietic neoplasms (excl leukaemias and lymphomas)
16.21.03      Myeloproliferative disorders (excl leukaemias)
16.21.03.004      Essential thrombocythaemia
01      Blood and lymphatic system disorders
01.13      Haematopoietic neoplasms (excl leukaemias and lymphomas)
01.13.03      Myeloproliferative disorders (excl leukaemias)
01.13.03.003      Essential thrombocythaemia
Description A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets. [MeSH]
MedDRA Code 10015493
MeSH ID D013920
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Essential thrombocythaemia | Essential thrombocythemia | Essential thrombocytosis | Ideopathic thrombocytosis | Idiopathic thrombocytosis | Primary hemorrhagic thrombocythemia | Primary haemorrhagic thrombocythaemia | Thrombocythemia, Essential | Essential Thrombocythemia | Essential Thrombocythemias | Thrombocythemias, Essential | Thrombocythemia, Hemorrhagic | Primary Thrombocythemia | Thrombocythemia, Primary | Primary Thrombocythemias | Thrombocythemias, Primary | Thrombocytosis, Primary | Primary Thrombocytoses | Primary Thrombocytosis | Thrombocytoses, Primary | Hemorrhagic Thrombocythemia | Hemorrhagic Thrombocythemias | Thrombocythemias, Hemorrhagic | Thrombocythemia, Idiopathic | Idiopathic Thrombocythemia | Idiopathic Thrombocythemias | Thrombocythemias, Idiopathic | Thrombocytosis, Autosomal Dominant | Autosomal Dominant Thrombocytoses | Autosomal Dominant Thrombocytosis | Dominant Thrombocytoses, Autosomal | Dominant Thrombocytosis, Autosomal | Thrombocytoses, Autosomal Dominant
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00139Anagrelide--
BADD_D00151Apixaban0.000043%
BADD_D00356Carbamazepine0.000186%
BADD_D01110Hydroxyurea0.000280%
BADD_D01136Imatinib0.000280%
BADD_D01281Levonorgestrel0.000473%
BADD_D01954Rivaroxaban0.000063%
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