Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Unexplained chronic cough | Refractory chronic cough | Coughs
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02392Zoledronic acid--
BADD_D02393Zolmitriptan--
BADD_D02394Zolpidem--
BADD_D02395Zolpidem tartrate--
BADD_D02396Zonisamide--
BADD_D02407Upadacitinib0.015793%
BADD_D02412Octreotide0.001863%
BADD_D02415Ziprasidone0.001387%
BADD_D02428Loperamide--
BADD_D02432Glycopyrronium0.008889%
BADD_D02439Levodopa0.039844%
BADD_D02443Tiotropium0.009017%
BADD_D02446Prasterone0.014812%
BADD_D02452Icatibant-
BADD_D02460Ganirelix0.000186%
BADD_D02464Fingolimod0.065028%
BADD_D02465Aclidinium0.003689%
BADD_D02470Nintedanib0.009727%
BADD_D02471Oxygen0.003098%
BADD_D02473Sodium chloride0.003403%
BADD_D02480Alectinib0.001836%
BADD_D02482Acalabrutinib--
BADD_D02483Ribociclib0.004824%
BADD_D02487Baricitinib0.005232%
BADD_D02492Deflazacort0.002592%
BADD_D02493Selinexor0.000627%
BADD_D02495Duvelisib0.000660%
BADD_D02498Abemaciclib--
BADD_D02509Brigatinib0.003224%
BADD_D02510Rucaparib0.008227%
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ADReCS-Target
ADR Term Drug Name Target