Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Unexplained chronic cough | Refractory chronic cough | Coughs
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01322Losartan0.000711%
BADD_D01323Losartan potassium--
BADD_D01326Loxapine--
BADD_D01328Lubiprostone0.004772%
BADD_D01336Macitentan0.038401%
BADD_D01345Magnevist--
BADD_D01349Mannitol--
BADD_D01352Maraviroc--
BADD_D01359Mechlorethamine0.001332%
BADD_D01371Megestrol--
BADD_D01372Megestrol acetate--
BADD_D01374Meloxicam0.000075%
BADD_D01375Meloxicam sodium--
BADD_D01376Melphalan0.000112%
BADD_D01378Memantine0.000810%
BADD_D01379Memantine hydrochloride--
BADD_D01381Mepact--
BADD_D01391Mercaptoethanesulfonic acid--
BADD_D01392Mercaptopurine--
BADD_D01393Meropenem0.000301%
BADD_D01394Merrem i.v.--
BADD_D01397Mesalamine0.003074%
BADD_D01398Mesna--
BADD_D01403Methacholine--
BADD_D01415Methocarbamol0.000165%
BADD_D01418Methotrexate--
BADD_D01419Methotrexate sodium--
BADD_D01420Methoxsalen0.000781%
BADD_D01421Methoxy polyethylene glycol-epoetin beta--
BADD_D01431Methylphenidate--
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ADReCS-Target
ADR Term Drug Name Target