Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Chronic fatigue syndrome
ADR ID BADD_A00928
ADR Hierarchy
11      Infections and infestations
11.07      Ancillary infectious topics
11.07.01      Inflammatory disorders following infection
11.07.01.020      Chronic fatigue syndrome
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.013      Chronic fatigue syndrome
Description A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9) [MeSH]
MedDRA Code 10008874
MeSH ID D015673
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Chronic fatigue syndrome | ME | Myalgic encephalomyelitis | Neuromyasthenia | Post viral debility | Post viral fatigue | Post-viral fatigue syndrome | Post-viral fatigue syndrome NOS | Royal Free disease | Post viral fatigue syndrome | Fatigue Syndrome, Chronic | Myalgic Encephalomyelitis | Encephalomyelitis, Myalgic | Chronic Fatigue Syndrome | Chronic Fatigue Syndromes | Fatigue Syndromes, Chronic | Chronic Fatigue-Fibromyalgia Syndrome | Chronic Fatigue Fibromyalgia Syndrome | Chronic Fatigue-Fibromyalgia Syndromes | Fatigue-Fibromyalgia Syndrome, Chronic | Fatigue-Fibromyalgia Syndromes, Chronic | Postviral Fatigue Syndrome | Infectious Mononucleosis-Like Syndrome, Chronic | Infectious Mononucleosis Like Syndrome, Chronic | Royal Free Disease | Chronic Fatigue and Immune Dysfunction Syndrome | Chronic Fatigue Disorder | Chronic Fatigue Disorders | Fatigue Disorder, Chronic | Fatigue Disorders, Chronic | Systemic Exertion Intolerance Disease | Fatigue Syndrome, Postviral | Fatigue Syndromes, Postviral | Postviral Fatigue Syndromes
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00284Bortezomib--
BADD_D00330Cabozantinib0.000246%
BADD_D00898Finasteride0.000247%
BADD_D01213Isotretinoin0.001158%
BADD_D01245Lansoprazole0.000099%
BADD_D01275Levofloxacin0.000148%
BADD_D01449Metronidazole0.000039%
BADD_D01496Montelukast0.000044%
BADD_D01598Ofloxacin0.000208%
BADD_D01831Prednisolone0.000035%
BADD_D02010Sertraline0.000019%
BADD_D02236Tofacitinib0.000530%
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