Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cardiospasm
ADR ID BADD_A00798
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.04      Gastrointestinal spastic and hypermotility disorders
07.02.04.007      Cardiospasm
Description A motility disorder of the ESOPHAGUS in which the LOWER ESOPHAGEAL SPHINCTER (near the CARDIA) fails to relax resulting in functional obstruction of the esophagus, and DYSPHAGIA. Achalasia is characterized by a grossly contorted and dilated esophagus (megaesophagus). [MeSH]
MedDRA Code 10007645
MeSH ID D004931
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Achalasia and cardiospasm | Cardiospasm | Esophageal Achalasia | Achalasias, Esophageal | Esophageal Achalasias | Cardiospasms | Achalasia | Achalasias | Achalasia, Esophageal | Megaesophagus
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00850Etodolac--
BADD_D01245Lansoprazole--
BADD_D01633Oxaliplatin0.000280%
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01683Paroxetine mesylate--
BADD_D02266Trazodone--
BADD_D02267Trazodone hydrochloride--
BADD_D02379Zaleplon--
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