Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Carcinoid tumour
ADR ID BADD_A00761
ADR Hierarchy
05      Endocrine disorders
05.08      Neoplastic and ectopic endocrinopathies
05.08.01      Endocrine neoplasms NEC
05.08.01.002      Carcinoid tumour
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.24      Endocrine neoplasms malignant and unspecified
16.24.04      Carcinoid tumours
16.24.04.002      Carcinoid tumour
Description A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182) [MeSH]
MedDRA Code 10007275
MeSH ID D002276
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Argentaffinoma | Carcinoid tumor | Carcinoid tumour | Carcinoid tumour NOS | Carcinoid Tumor | Carcinoid Tumors | Tumor, Carcinoid | Tumors, Carcinoid | Carcinoid | Carcinoids | Carcinoid, Goblet Cell | Carcinoids, Goblet Cell | Goblet Cell Carcinoid | Goblet Cell Carcinoids | Argentaffinomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00858Everolimus0.000459%
BADD_D01245Lansoprazole0.000099%
BADD_D01401Metformin0.000014%
BADD_D01614Omeprazole--
BADD_D01913Ranitidine0.000113%
BADD_D02100Sunitinib0.001041%
BADD_D02331Valsartan--
BADD_D02412Octreotide0.000652%
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