Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Arteriosclerosis
ADR ID BADD_A00333
ADR Hierarchy
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.02      Non-site specific necrosis and vascular insufficiency NEC
24.04.02.001      Arteriosclerosis
Description Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries. [MeSH]
MedDRA Code 10003210
MeSH ID D001161; D050197; D058226
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Arteriosclerosis | Atherosclerosis | Atherosclerosis generalized | Atherosclerosis of other specified arteries | Generalized and unspecified atherosclerosis | Generalized arteriosclerosis | Generalized atheroma | Hyperplastic atherosclerosis | Nodular atherosclerosis | Atheroma | Arteriosclerotic cardiovascular disease | Atherosclerotic cardiovascular disease | Vascular atheroma | Arterial calcification | Atheromatosis | Atherosclerosis generalised | Generalised arteriosclerosis | Generalised atheroma | Atherosclerotic plaque | Hyaline arteriolosclerosis | Complicated atherosclerosis | Calcified atherosclerotic plaque | Arterioscleroses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01188Ioxaglic acid--
BADD_D01257Letrozole0.000659%
BADD_D01260Leuprolide acetate0.001434%
BADD_D01378Memantine--
BADD_D01401Metformin0.000024%
BADD_D01445Metoprolol0.000013%
BADD_D01470Minocycline0.000118%
BADD_D01567Nilotinib0.015468%
BADD_D01653Paclitaxel0.000168%
BADD_D01799Ponatinib0.000470%
BADD_D01804Posaconazole--
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01822Prasugrel0.000384%
BADD_D01831Prednisolone0.000227%
BADD_D01834Prednisone0.000013%
BADD_D01835Pregabalin--
BADD_D01915Ranolazine0.000284%
BADD_D01933Ribavirin0.005934%
BADD_D01966Ropinirole--
BADD_D01970Rosiglitazone maleate--
BADD_D01971Rosuvastatin0.000034%
BADD_D02018Sildenafil0.000290%
BADD_D02026Simvastatin0.000015%
BADD_D02029Sitagliptin0.000292%
BADD_D02047Sodium oxybate0.000536%
BADD_D02098Sumatriptan--
BADD_D02099Sumatriptan succinate--
BADD_D02105Tacrolimus0.000446%
BADD_D02170Testosterone0.000500%
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ADReCS-Target
ADR Term Drug Name Target