Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Aortic stenosis
ADR ID BADD_A00284
ADR Hierarchy
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.01      Aortic necrosis and vascular insufficiency
24.04.01.001      Aortic stenosis
Description A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA. [MeSH]
MedDRA Code 10002906
MeSH ID D001024
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Aortic stenosis | Aortic stricture | Aorto-iliac arterial stenosis | Abdominal aortic stenosis | Mid aortic syndrome | Aortic arch stenosis | Thoracic aortic stenosis | Aortic Valve Stenosis | Aortic Valve Stenoses | Stenoses, Aortic Valve | Stenosis, Aortic Valve | Valve Stenoses, Aortic | Valve Stenosis, Aortic | Aortic Stenosis | Stenoses, Aortic | Stenosis, Aortic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01834Prednisone0.000027%
BADD_D01915Ranolazine0.000284%
BADD_D01954Rivaroxaban0.000760%
BADD_D02010Sertraline0.000019%
BADD_D02029Sitagliptin0.000106%
BADD_D02047Sodium oxybate0.000268%
BADD_D02066Spironolactone0.000055%
BADD_D02105Tacrolimus0.001188%
BADD_D02106Tadalafil0.000429%
BADD_D02107Tafamidis0.001346%
BADD_D02192Thalidomide0.000362%
BADD_D02241Tolcapone--
BADD_D02268Treprostinil--
BADD_D02325Valdecoxib--
BADD_D02329Valproic acid0.000100%
BADD_D02344Vemurafenib0.000112%
BADD_D02373Warfarin0.000070%
BADD_D02443Tiotropium0.000115%
BADD_D02490Apalutamide0.000334%
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