Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Acute disseminated encephalomyelitis
ADR ID BADD_A00072
ADR Hierarchy
10      Immune system disorders
10.04      Autoimmune disorders
10.04.10      Nervous system autoimmune disorders
10.04.10.010      Acute disseminated encephalomyelitis
17      Nervous system disorders
17.16      Demyelinating disorders
17.16.02      Demyelinating disorders NEC
17.16.02.003      Acute disseminated encephalomyelitis
Description An acute or subacute inflammatory process of the CENTRAL NERVOUS SYSTEM characterized histologically by multiple foci of perivascular demyelination. Symptom onset usually occurs several days after an acute viral infection or immunization, but it may coincide with the onset of infection or rarely no antecedent event can be identified. Clinical manifestations include CONFUSION, somnolence, FEVER, nuchal rigidity, and involuntary movements. The illness may progress to COMA and eventually be fatal. (Adams et al., Principles of Neurology, 6th ed, p921) [MeSH]
MedDRA Code 10000709
MeSH ID D004673
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acute disseminated encephalomyelitis | Perivenous encephalomyelitis | Encephalomyelitis, Acute Disseminated | Disseminated Encephalomyelitis, Acute | Acute Disseminated Encephalomyelitis | Acute Disseminated Encephalomyelitides | Disseminated Encephalomyelitides, Acute | Encephalomyelitides, Acute Disseminated | Encephalomyelitis, Postexanthem | Postexanthem Encephalomyelitis | Postinfectious Encephalomyelitis | Encephalomyelitis, Postinfectious | Encephalitis, Post-Vaccinal | Encephalitis, Post Vaccinal | Post-Vaccinal Encephalomyelitis | Encephalomyelitides, Post-Vaccinal | Encephalomyelitis, Post-Vaccinal | Post Vaccinal Encephalomyelitis | Post-Vaccinal Encephalomyelitides | Post-Vaccinal Encephalitis | Encephalitides, Post-Vaccinal | Post Vaccinal Encephalitis | Post-Vaccinal Encephalitides | Encephalitis, Postvaccinal | Encephalitis, Vaccination | Vaccination Encephalitis | Postvaccinal Encephalitis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00899Fingolimod hydrochloride--
BADD_D01449Metronidazole0.000026%
BADD_D02105Tacrolimus0.000297%
BADD_D02464Fingolimod0.000482%
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