Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Acebutolol hydrochloride
Drug ID BADD_D00020
Description A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Indications and Usage For the management of hypertension and ventricular premature beats in adults.
Marketing Status Prescription; Discontinued
ATC Code C07AB04
DrugBank ID DB01193
KEGG ID D00597
MeSH ID D000070
PubChem ID 441307
TTD Drug ID D0HD9K
NDC Product Code 53746-670; 10135-630; 52932-0719; 65162-670; 51927-2906; 50268-050; 65162-669; 68069-0009; 58159-081; 10135-631; 53746-669
Synonyms Acebutolol | Acetobutolol | Acebutolol Hydrochloride | M&B-17803 A | M&B 17803 A | M&B17803 A | M & B 17803A | Neptal | Prent | Rhotral | Sectral | Monitan | Apo-Acebutolol | Apo Acebutolol | ApoAcebutolol | Novo-Acebutolol | Novo Acebutolol | NovoAcebutolol
Chemical Information
Molecular Formula C18H29ClN2O4
CAS Registry Number 34381-68-5
SMILES CCCC(=O)NC1=CC(=C(C=C1)OCC(CNC(C)C)O)C(=O)C.Cl
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abnormal dreams17.15.02.001; 19.02.03.001--Not Available
Agranulocytosis01.02.03.001--Not Available
Alanine aminotransferase increased13.03.01.003--
Alopecia23.02.02.001--
Amnesia17.03.02.001; 19.20.01.001--
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Aspartate aminotransferase increased13.03.01.006--
Atrioventricular block02.03.01.002--Not Available
Back pain15.03.04.005--
Blood bilirubin increased13.03.01.008--
Blood lactate dehydrogenase increased13.04.02.002--
Bradycardia02.03.02.002--Not Available
Cardiac failure02.05.01.001--
Catatonia19.11.01.001--Not Available
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.003--Not Available
Chromaturia20.02.01.002--
Colitis ischaemic07.08.01.004; 24.04.08.012--Not Available
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Cough22.02.03.001--
Depressed level of consciousness17.02.04.002--
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
Dry eye06.08.02.001--
Dyspepsia07.01.02.001--
Dyspnoea02.01.03.002; 22.02.01.004--
Dysuria20.02.02.002--
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