Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cerebral small vessel ischaemic disease
ADR ID BADD_A09087
ADR Hierarchy
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.06      Cerebrovascular and spinal necrosis and vascular insufficiency
24.04.06.034      Cerebral small vessel ischaemic disease
17      Nervous system disorders
17.08      Central nervous system vascular disorders
17.08.02      Central nervous system vascular disorders NEC
17.08.02.020      Cerebral small vessel ischaemic disease
Description Pathological processes or diseases where cerebral MICROVESSELS show abnormalities. They are often associated with aging, hypertension and risk factors for lacunar infarcts (see LACUNAR INFARCTION); LEUKOARAIOSIS; and CEREBRAL HEMORRHAGE. [MeSH]
MedDRA Code 10070878
MeSH ID D059345
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cerebral small vessel ischaemic disease | Cerebral small vessel ischemic disease | White matter ischaemia | White matter ischemia | Ischaemic leukoencephalopathy | Ischemic leukoencephalopathy | Covert brain infarct | Cerebral small vessel disease | Cerebral Small Vessel Diseases | Cerebral Small Vessel Disease | Cerebral Microangiopathies | Cerebral Microangiopathy | Microangiopathies, Cerebral | Microangiopathy, Cerebral
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000088%
BADD_D01253Lenalidomide0.000241%
BADD_D01567Nilotinib0.000168%
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