Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02281Trifluoperazine--
BADD_D02282Trifluoperazine hydrochloride--
BADD_D02284Trihexyphenidyl--
BADD_D02285Trihexyphenidyl hydrochloride--
BADD_D02290Trimethoprim--
BADD_D02294Trimipramine--
BADD_D02295Trimipramine maleate--
BADD_D02297Triptorelin--
BADD_D02298Triptorelin pamoate--
BADD_D02303Tropicamide--
BADD_D02304Tropisetron--
BADD_D02305Trospium--
BADD_D02306Trospium chloride--
BADD_D02307Trovafloxacin--
BADD_D02308Trovafloxacin mesylate--
BADD_D02312Ulipristal--
BADD_D02319Urofollitropin--
BADD_D02321Ursodiol--
BADD_D02324Valacyclovir hydrochloride--
BADD_D02325Valdecoxib--
BADD_D02326Valganciclovir--
BADD_D02327Valganciclovir hydrochloride--
BADD_D02328Valproate sodium--
BADD_D02329Valproic acid--
BADD_D02331Valsartan--
BADD_D02332Vancomycin--
BADD_D02334Vandetanib0.000302%
BADD_D02337Varenicline--
BADD_D02338Varenicline tartrate--
BADD_D02344Vemurafenib--
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