Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01979Sacrosidase--
BADD_D01980Salicylic acid--
BADD_D01981Salmeterol--
BADD_D01989Saquinavir mesylate--
BADD_D01990Sargramostim--
BADD_D01992Saxagliptin0.001048%
BADD_D01994Scopolamine--
BADD_D01995Scopolamine hydrobromide--
BADD_D01996Sebelipase alfa--
BADD_D01997Secobarbital--
BADD_D01998Secobarbital sodium--
BADD_D02002Selegiline--
BADD_D02003Selegiline hydrochloride--
BADD_D02007Semaxanib--
BADD_D02010Sertraline--
BADD_D02011Sertraline hydrochloride--
BADD_D02012Sevelamer--
BADD_D02013Sevelamer carbonate--
BADD_D02014Sevelamer hydrochloride--
BADD_D02016Sibutramine--
BADD_D02017Sibutramine hydrochloride--
BADD_D02018Sildenafil--
BADD_D02020Silodosin0.001923%
BADD_D02021Siltuximab--
BADD_D02025Simeprevir--
BADD_D02026Simvastatin--
BADD_D02028Sirolimus--
BADD_D02029Sitagliptin0.001857%
BADD_D02030Sitagliptin phosphate--
BADD_D02031Sitaxentan--
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